The dried, ground rhizome of turmeric (Curcuma longa) has been used in Asian medicine for centuries. This perennial plant in the ginger family is cultivated throughout the tropics and is used as both a spice and to support health. Curcumin is a term that is sometimes used to refer to any or all of the curcuminoid compounds in turmeric. There are three main curcuminoids in turmeric, of which curcumin (diferuloylmethane) is the best studied. Other curcuminoids in turmeric include demethoxycurcumin and bisdemethoxycurcumin. Curcumin imparts yellow color to the rhizome.
Not all supplements, or nutritional extracts are bioavailable, or absorbable, by your body. If a product cannot be absorbed by your body, it really doesn’t matter how much you take as there will be no clinical effect.
In humans, curcumin is very poorly absorbed, rapidly metabolized, and quickly eliminated. Once in the plasma, however, curcumin is quite stable and even available to hard-to-reach tissues, such as the brain.16
The challenge, therefore, has been to find a way to stabilize curcuminoids in the gut and deliver them to the plasma without the use of synthetic agents or substances that are potentially harmful or undesirable.
Turmeric, or curcumin, products vary greatly from company to company. Suggestions have been made to use concurrently with black pepper to enhance bioavailability, but again, that will have very little effect on absorption if the supplement is not a high-quality curcumin extract that can get into the plasma.
- Standard curcumin is poorly absorbed even at high doses. Unlike other forms of curcumin, Theracurmin is water-dispersible, meaning it dissolves quickly and maintains solubility over time, thereby improving curcumin’s overall absorption.
- Theracurmin is a novel preparation of turmeric that utilizes patented, natural colloidal dispersion technology to enhance bioavailability and dramatically increase curcumin levels in the blood.
- This translates to being over 27 times more bioavailable than standard curcumin products.1
- High absorbability and bioavailability suggests Theracurmin supplementation can maximize curcumin’s biological effects in the body.
What effect does curcumin have in your body?
Scientific publications on curcumin in the medical literature number in the thousands, and continue to grow.
Among many observed biochemical effects on pain and inflammation:
- Potent anti-inflammatory and anti-oxidant – Inhibits arachidonic acid metabolism via lipoxygenase and scavenging of free radicals generated in this pathway.2
- Part of the curcumin molecule is important for activation of the transient receptor potential vanilloid 1 (TRPV1, also known as the capsaicin receptor), which plays an important role in pain perception, or nociception. Experimental research indicates that curcumin blocks TRPV1 activation and thereby inhibits TRPV1-mediated pathways.3
- Supports cell signaling – Has been shown to down regulate COX-2 enzyme pathways to work as a selective anti-inflammatory.4
- Improved liver function and detoxification
- Increased skin moisture (great for those of us living in the desert!)
- Enhanced muscular recovery after endurance exercise
- Effects on improving mental cognition are being studied
- Menon VP, Sudheer AR. Adv Exp Med Biol. 2007;595:105–25.
- Liu JY, Lin SJ, Lin JK. Carcinogenesis. 1993 May;14(5):857–61
- Yeon KY, Kim SA, Kim YH, et al. J Dent Res. 2010;89(2):170–4
- Surh YJ, Chun KS, Cha HH, et al. Mutat Res. 2001 Sep 1;480-481:243–68.
* These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. You should always consult with your health care provider before taking any new supplement.